Article

Metastatic organotropism in small cell lung cancer

2024-10-08

Abstract excerpt

Metastasis is the leading cause of cancer-related deaths, yet its regulatory mechanisms are not fully understood. Small-cell lung cancer (SCLC) is the most metastatic form of lung cancer, with most patients presenting with widespread disease, making it an ideal model for studying metastasis. However, the lack of suitable preclinical models has limited such studies. We utilized rapid autopsy-derived tumors to devel...

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Literature Corpus work: 5f2303c5-d60b-58f0-976f-342735c3933e
DOI: 10.1101/2024.10.07.617066

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