Article

The Effect of <i>N</i>-Glycosylation of SARS COV-2 Spike Protein on the Virus Interaction With the Host Cell ACE2 Receptor

2021-06-01

Abstract excerpt

The densely glycosylated spike (S) protein highly exposed on severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) surface mediates host cell entry by binding to the receptor angiotensin-converting enzyme 2 (ACE2). However, the role of glycosylation has not been fully understood. In the present study, we investigated the effect of different <i>N</i>-glycosylation of S1 protein on its binding to ACE2. Using...

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Literature Corpus work: 830c3900-3e08-5550-9515-751459b39dbe
DOI: 10.2139/ssrn.3858064

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