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Structural remodeling of SARS-CoV-2 spike protein glycans reveals the regulatory roles in receptor binding affinity

2021-08-27

Abstract excerpt

Glycans of the SARS-CoV-2 spike protein are speculated to play functional roles in the infection processes as they extensively cover the protein surface and are highly conserved across the variants. To date, the spike protein has become the principal target for vaccine and therapeutic development while the exact effects of its glycosylation remain elusive. Experimental reports have described the heterogeneity of t...

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Identifiers and source

Literature Corpus work
69327f35-8d36-535c-b3da-3d3de1afb7b0
DOI
10.1101/2021.08.26.457782
Open publication

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Structural remodeling of SARS-CoV-2 spike protein glycans reveals the regulatory roles in receptor binding affinityDOI 10.1101/2021.08.26.457782
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