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Article

Coxiella burnetii effector CvpB modulates phosphoinositide metabolism for optimal vacuole development.

Proceedings of the National Academy of Sciences of the United States of America - 7 Jun 2016

Martinez Eric, Allombert Julie, Cantet Franck, Lakhani Anissa, Yandrapalli Naresh, Neyret Aymeric, Norville Isobel H, Favard Cyril, Muriaux Delphine, Bonazzi Matteo

Abstract excerpt

The Q fever bacterium Coxiella burnetii replicates inside host cells within a large Coxiella-containing vacuole (CCV) whose biogenesis relies on the Dot/Icm-dependent secretion of bacterial effectors. Several membrane trafficking pathways contribute membranes, proteins, and lipids for CCV biogenesis. These include the endocytic and autophagy pathways, which are characterized by phosphatidylinositol 3-phosphate...

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Identifiers

PMID: 27226300
DOI: 10.1073/pnas.1522811113
PMCID: PMC4988616

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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