A Comparative Study of RT-PCR, FISH, and Karyotyping for t(9;22) Positive Leukemias, and Their Outcomes in Pediatric Patients in a Low Middle-Income Country (LMIC)

Abstract excerpt

<title>Abstract</title> <p><bold>Objectives:</bold> Various diagnostic tests are available for detecting t(9;22) transcripts in acute and chronic leukemia. This study aims to determine the most effective and cost-efficient testing strategy. Additionally, we analyzed the outcomes of Ph+ leukemias in our population. <bold>Methods:</bold> Retrospective cohort study was conducted at a tertiary care center in a LMIC....

Topics

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• Child, Preschool
• Cost-Benefit Analysis
• Developing Countries
• Fusion Proteins, bcr-abl
• High-Throughput Nucleotide Sequencing
• Mutation
• Philadelphia Chromosome
• Precursor B-Cell Lymphoblastic Leukemia-Lymphoma

Identifiers and source

Literature Corpus work

82a97f84-4d64-5088-aa15-3d988f94574d

DOI

10.21203/rs.3.rs-4498715/v1