Real-Life Data of Patients with Chronic Myeloid Leukemia in Amazonas

Abstract excerpt

<title>Abstract</title> <p> Background Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm caused by the (t9;22) (q34;q11.2) translocation, known as the Philadelphia chromosome (Ph+), which generates the <italic>BCR::ABL1</italic> fusion oncogene. This oncogene is central to CML pathogenesis. The disease accounts for 15% of adult leukemias, predominantly affecting males, with a median diagnosis ag...

Topics

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• Acute Lymphoblastic Leukemia research
• Algorithms
• Chronic Lymphocytic Leukemia Research
• Chronic Myeloid Leukemia Treatments
• fms-Like Tyrosine Kinase 3
• Leukemia, Myeloid, Acute
• Mutation
• World Health Organization

Identifiers and source

Literature Corpus work

3e349266-80d9-534c-a741-3274680c26e5

DOI

10.21203/rs.3.rs-8263850/v1