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Article

Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events.

Nature communications - 25 Oct 2016

Ashouri Arghavan, Sayin Volkan I, Van den Eynden Jimmy, Singh Simranjit X, Papagiannakopoulos Thales, Larsson Erik

Abstract excerpt

Thousands of long non-coding RNAs (lncRNAs) lie interspersed with coding genes across the genome, and a small subset has been implicated as downstream effectors in oncogenic pathways. Here we make use of transcriptome and exome sequencing data from thousands of tumours across 19 cancer types, to identify lncRNAs that are induced or repressed in relation to somatic mutations in key oncogenic driver genes. Our...

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Identifiers

PMID: 28959951
DOI: 10.1038/ncomms13197
PMCID: PMC5093340

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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