Article

The natural HLA-Peptidome of Sezary Syndrome: uncovering antigens for T cell-based immunotherapy

2024-12-25

Abstract excerpt

Sezary syndrome (SS) is a rare and aggressive form of cutaneous T-cell lymphoma, that has a poor prognosis, with a median overall survival time of less than 3 years. Despite advances in its treatment, SS is a challenge to manage, often characterized by high rates of relapse and limited response to therapy in many patients. The main challenge for treatment, including vaccine development is its heterogeneity. In its...

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Literature Corpus work: 82903226-3239-5032-a41b-a299814b0cf5
DOI: 10.1101/2024.12.25.630030

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