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Personalized treatment of Sézary syndrome by targeting a novel <i><scp>CTLA</scp>4</i>:<i><scp>CD</scp>28</i> fusion

27 Nov 2014

Abstract excerpt

Matching molecularly targeted therapies with cancer subtype-specific gene mutations is revolutionizing oncology care. However, for rare cancers this approach is problematic due to the often poor understanding of the disease's natural history and phenotypic heterogeneity, making treatment of these cancers a particularly unmet medical need in clinical oncology. Advanced Sézary syndrome (SS), an aggressive,...

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PMID: 25802883
DOI: 10.1002/mgg3.121

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