Primary Sjögren's syndrome: clinical phenotypes, outcome and the development of biomarkers.

doi:10.1007/s12026-016-8844-4

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Article

Primary Sjögren's syndrome: clinical phenotypes, outcome and the development of biomarkers.

Immunologic research - 1 Feb 2017

Goules Andreas V, Tzioufas Athanasios G

Abstract excerpt

Primary Sjögren's syndrome is a complex, autoimmune disease with distinct clinical phenotypes and variable outcomes. The systemic form of the disease is characterized by immune complex-mediated manifestations and is complicated by lymphoma as a result of a polyclonal B cell hyperactivity that is evolving into B cell malignancy. In the past decades, well-established clinical and serological markers have been...

Topics

Biomarkers
Humans
Phenotype
Risk Factors
Sjogren's Syndrome
Treatment Outcome

Source

Open in PubMed

Identifiers

PMID: 27444892
DOI: 10.1007/s12026-016-8844-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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