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The rapid drop of metronidazole concentration in TYI-S-33 culture medium without Giardia trophozoites

2026-07-13

Abstract excerpt

<title>Abstract</title> <p> In our effort to generate metronidazole (MTZ)-resistant <italic>Giardia</italic> lines to analyze the genetic mechanisms underlying the emergence of giardiasis refractory to 5-nitroimidazoles in clinical cases, we obtained unusual results. For this reason, we determined the effective MTZ concentration in TYI-S-33 culture medium, with and without <italic>Giardia intestinalis</italic...

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Literature Corpus work
82894dc9-5349-5ffd-bdcb-2c76c64460a8
DOI
10.21203/rs.3.rs-9869431/v1
Open publication

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