Article

Multiparametric analysis of sperm chromatin and ROS reveals the existence of subpopulations that are linked to embryo development after ICSI

2026-04-24

Abstract excerpt

<title>Abstract</title> <p> Sperm DNA damage is known to be linked to fertility potential, yet the structural integrity of sperm chromatin has received less attention in the male factor research. The objective of this work is to develop a multiparametric test to simultaneously assess chromatin protamination, chromatin condensation, reactive oxygen species (ROS), and viability in human sperm; to explore whether s...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 82538aff-26d3-5c00-9a2f-15af623ff62e
DOI: 10.21203/rs.3.rs-9079231/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Multiparametric analysis of sperm chromatin and ROS reveals the existence of subpopulations that are linked to embryo development after ICSIDOI 10.21203/rs.3.rs-9079231/v1Read

Condensation and protamination of sperm chromatin affect ICSI outcomes when gametes from healthy individuals are usedSemantic proximity Read

Toxicants and human sperm chromatin integritySemantic proximity Read

Comparative analysis of tests used to assess sperm chromatin integrity and DNA fragmentationSemantic proximity Read

Sperm DNA: organization, protection and vulnerability: from basic science to clinical applications--a position reportSemantic proximity Read

Protamines and DNA integrity as a biomarkers of sperm quality and assisted conception outcomeSemantic proximity Read

Sperm chromatin: Evaluation, epigenetic signatures and relevance for embryo development and assisted reproductive technology outcomesSemantic proximity Read

Sperm chromatin structure assay (SCSA®).Semantic proximity Read

Assessing sperm chromatin and <scp>DNA</scp> damage: clinical importance and development of standardsSemantic proximity Read

Effect of human sperm chromatin anomalies on fertilization outcome post-ICSISemantic proximity Read

Chromatin condensation, fragmentation of DNA and differences in the epigenetic signature of infertile menSemantic proximity Read

Sperm Chromatin Structure Assay for Fertility AssessmentSemantic proximity Read

Relationship of DNA integrity to HRG C633T SNP and ART outcome in infertile couples.Semantic proximity Read