Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Condensation and protamination of sperm chromatin affect ICSI outcomes when gametes from healthy individuals are used

20 Dec 2022

Abstract excerpt

STUDY QUESTION: Do defects in sperm chromatin protamination and condensation have an impact on ICSI outcomes? SUMMARY ANSWER: Sperm protamination is related to fertilization rates in healthy donors, and the in vitro capacity of sperm to condense their chromatin is linked to blastocyst rates, both associations being more apparent in women <33 years of age. WHAT IS KNOWN ALREADY: Previous data on how sperm...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ovarian function and disorders
Share to Reproductive Biology and Fertility
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36539233
DOI: 10.1093/humrep/deac261

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Condensation and protamination of sperm chromatin affect ICSI outcomes when gametes from healthy individuals are usedPMID 36539233Read ↗

Multiparametric analysis of sperm chromatin and ROS reveals the existence of subpopulations that are linked to embryo development after ICSISemantic proximity Read ↗

Effect of human sperm chromatin anomalies on fertilization outcome post-ICSISemantic proximity Read ↗

Sperm chromatin: Evaluation, epigenetic signatures and relevance for embryo development and assisted reproductive technology outcomesSemantic proximity Read ↗

Sperm DNA integrity does play a crucial role for embryo development after ICSI, notably when good-quality oocytes from young donors are usedSemantic proximity Read ↗

Toxicants and human sperm chromatin integritySemantic proximity Read ↗

H3K4me2 accompanies chromatin immaturity in human spermatozoa: an epigenetic marker for sperm quality assessmentSemantic proximity Read ↗

Comparative analysis of tests used to assess sperm chromatin integrity and DNA fragmentationSemantic proximity Read ↗

Sperm chromatin damage impairs human fertilitySemantic proximity Read ↗

Insights into the sperm chromatin and implications for male infertility from a protein perspectiveSemantic proximity Read ↗

Human Sperm Morphology as a Marker of Its Nuclear Quality and Epigenetic PatternSemantic proximity Read ↗

Sperm DNA damage diagnostics: when and whySemantic proximity Read ↗

Protamines and DNA integrity as a biomarkers of sperm quality and assisted conception outcomeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.