Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Toxicants and human sperm chromatin integrity

7 Oct 2009

Abstract excerpt

The integrity of the paternal genome is essential as the spermatozoon can bring genetic damage into the oocyte at fertilization and contribute to the development of abnormal pregnancy outcome. During the past two decades, many assays have been developed to measure sperm DNA strand breaks, chromatin structure and compaction and assess the proteins associated with the DNA, as well as epigenetic modifications. Using...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Renal and related cancers
Share to Reproductive Biology and Fertility
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19812089
DOI: 10.1093/molehr/gap087

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Toxicants and human sperm chromatin integrityPMID 19812089Read ↗

Chromatin condensation, fragmentation of DNA and differences in the epigenetic signature of infertile menSemantic proximity Read ↗

Sperm DNA: organization, protection and vulnerability: from basic science to clinical applications--a position reportSemantic proximity Read ↗

Environmental toxicants cause sperm DNA fragmentation as detected by the Sperm Chromatin Structure Assay (SCSA)Semantic proximity Read ↗

Sperm DNA damage diagnostics: when and whySemantic proximity Read ↗

Are sperm chromatin and DNA defects relevant in the clinic?Semantic proximity Read ↗

Etiologies of sperm DNA damage and its impact on male infertilitySemantic proximity Read ↗

Sperm DNA damage and its impact on male reproductive health: a critical review for clinicians, reproductive professionals and researchersSemantic proximity Read ↗

Single and Double Strand Sperm DNA Damage: Different Reproductive Effects on Male FertilitySemantic proximity Read ↗

Assessing sperm chromatin and <scp>DNA</scp> damage: clinical importance and development of standardsSemantic proximity Read ↗

Role of sperm chromatin abnormalities and DNA damage in male infertilitySemantic proximity Read ↗

Should we be measuring DNA damage in human spermatozoa? New light on an old questionSemantic proximity Read ↗

The effects of endocrine disruptors on the male germline: an intergenerational health riskSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.