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Article

Chromatin condensation, fragmentation of DNA and differences in the epigenetic signature of infertile men

3 Nov 2018

Abstract excerpt

Epidemiological studies report an increase of pathologies of male reproductive tracts and suggest a link between this trend and the increased exposure of men to endocrine disruptors (EDs). The mechanisms by which EDs impact male fertility are far to be elucidated although DNA, chromatin and epigenome of spermatozoa appear to be relevant targets for these molecules. Indeed, many studies report associations between...

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Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
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PMID: 30420311
DOI: 10.1016/j.beem.2018.10.004

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