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Sperm Chromatin Structure Assay for Fertility Assessment

1 Jul 2000

Abstract excerpt

Abstract The integrity of mammalian sperm DNA is of prime importance for the paternal genetic contribution to normal offspring. Damaged DNA in the single sperm that fertilizes the female egg can have a dramatic negative impact on fetal development. This comprehensive and detailed unit presents a rapid, reliable, practical test for DNA integrity based on staining with acridine orange. SCSA data have been...

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PMID: 18770725
DOI: 10.1002/0471142956.cy0713s13

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