Article

BRD9 inhibition induces selective radiosensitivity in glioblastoma through MYC pathway modulation

2026-08-11

Abstract excerpt

<h4>ABSTRACT</h4> Radiotherapy (RT) is a cornerstone of glioblastoma (GBM) treatment, yet therapeutic resistance remains nearly universal due to the rapid activation of stress-adaptive survival programs. Identifying molecular regulators that sustain these adaptive responses may reveal context-dependent vulnerabilities that can be therapeutically exploited. Here, we performed an epigenetic drug screen under low-do...

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Literature Corpus work: 8217cfbe-2997-5382-8064-392ba94eb28b
DOI: 10.64898/2026.08.10.741731

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