Article

Role of DEPDC1 in Glioblastoma Malignant Phenotype and Radiosensitivity

2025-05-28

Abstract excerpt

Radiotherapy has significantly improved survival outcomes in glioblastoma (GBM) patients, particularly when combined with tumor resection and temozolomide chemotherapy. However, radioresistance remains a major obstacle, limiting further advances in prognosis and potential cure. DEPDC1, a gene implicated in various malignant phenotypes, has not yet been investigated for its role in GBM radioresistance, despite sugg...

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Literature Corpus work: f1176d58-e7b2-570c-bbb8-9d6b1fa866a0
DOI: 10.1101/2025.05.25.655961

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