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Causal relationships between gut microbiome and hundreds of age-related traits: evidence of a replicable effect on ApoM protein levels

2025-02-03

Abstract excerpt

In the past 20 years, the involvement of gut microbiome in human health has received particular attention, but its contribution to age-related diseases remains unclear. To address this, we performed a comprehensive two-sample Mendelian randomization investigation, testing 55130 potential causal relationships between 37 traits representing gut microbiome composition and function and age-related phenotypes, includin...

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Literature Corpus work
81e3c8b3-9d38-598b-aa74-1b11bd264403
DOI
10.1101/2025.02.03.25321568
Open publication

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Causal relationships between gut microbiome and hundreds of age-related traits: evidence of a replicable effect on ApoM protein levelsDOI 10.1101/2025.02.03.25321568
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