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A proteogenomic signature of age-related macular degeneration in blood

13 Jun 2022

Abstract excerpt

Age-related macular degeneration (AMD) is one of the most common causes of visual impairment in the elderly, with a complex and still poorly understood etiology. Whole-genome association studies have discovered 34 genomic regions associated with AMD. However, the genes and cognate proteins that mediate the risk, are largely unknown. In the current study, we integrate levels of 4782 human serum proteins with all...

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PMID: 35697682
DOI: 10.1038/s41467-022-31085-x

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