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Article

Human genetic determinants of the gut microbiome and their associations with health and disease: a phenome-wide association study.

Scientific reports - 8 Sept 2020

Groot Hilde E, van de Vegte Yordi J, Verweij Niek, Lipsic Erik, Karper Jacco C, van der Harst Pim

Abstract excerpt

Small-scale studies have suggested a link between the human gut microbiome and highly prevalent diseases. However, the extent to which the human gut microbiome can be considered a determinant of disease and healthy aging remains unknown. We aimed to determine the spectrum of diseases that are linked to the human gut microbiome through the utilization of its genetic determinants as a proxy for its composition. 180...

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Identifiers

PMID: 32901066
DOI: 10.1038/s41598-020-70724-5
PMCID: PMC7479141

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