Article

Lactate Metabolism Regulates Tumour Growth and Progression in Glioblastoma

2021-10-19

Abstract excerpt

<title>Abstract</title> <p><bold>Background.</bold> Tumor microenvironment (TME) plays a pivotal role in establishing malignancy and it is associated with high glycolytic metabolism and increased lactate production accumulating in TME through monocarboxylate transporters (MCTs). Several lines of evidence suggest that lactate also serves as a signalling molecule through its receptor HCAR1thus functioning as a para...

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Identifiers and source

Literature Corpus work: 81dc9daf-927a-567b-ae57-0049381b2448
DOI: 10.21203/rs.3.rs-965025/v1

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