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Metabolism and signaling crosstalk in glioblastoma progression and therapy resistance

18 Dec 2023

Abstract excerpt

Glioblastoma is the most common form of primary malignant brain tumor in adults and one of the most lethal human cancers, with high recurrence and therapy resistance. Glioblastoma cells display extensive genetic and cellular heterogeneity, which precludes a unique and common therapeutic approach. The standard of care in glioblastoma patients includes surgery followed by radiotherapy plus concomitant temozolomide....

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PMID: 38105543
DOI: 10.1002/1878-0261.13571

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