Article
The monocarboxylate transporter family--role and regulation.
IUBMB life - 1 Feb 2012
Halestrap Andrew P, Wilson Marieangela C
Abstract excerpt
Monocarboxylate transporter (MCT) isoforms 1-4 catalyze the proton-linked transport of monocarboxylates such as L-lactate across the plasma membrane, whereas MCT8 and MCT10 are thyroid hormone and aromatic amino acid transporters, respectively. The importance of MCTs is becoming increasingly evident as their extensive physiological and pathological roles are revealed. MCTs 1-4 play essential metabolic roles in...
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