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Structures of the germline-specific Deadhead and Thioredoxin T proteins from <i>Drosophila melanogaster</i> reveal unique features among Thioredoxins

2020-07-29

Abstract excerpt

<h4>ABSTRACT</h4> Thioredoxins (Trxs) are ubiquitous enzymes that regulate the redox state in cells. In Drosophila , there are two germline-specific Trxs, Deadhead (Dhd) and TrxT. Both proteins belong to the L(3)mbt malignant brain tumor signature and to the MMS survival network of genes that mediate the cellular response to DNA damage. Dhd is a maternal protein required for early embryogenesis that promotes pro...

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Literature Corpus work
81dba34a-b532-5b02-9c57-30c6c6f66eb3
DOI
10.1101/2020.07.29.226944
Open publication

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Structures of the germline-specific Deadhead and Thioredoxin T proteins from <i>Drosophila melanogaster</i> reveal unique features among ThioredoxinsDOI 10.1101/2020.07.29.226944
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