Article

Identification of novel causative genes of childhood epileptic encephalopathies

2023-07-27

Abstract excerpt

<h4>Background: </h4> and Objectives: Epileptic encephalopathy is a devastating epilepsy with etiologies largely elusive, despite recent whole gene/exon sequencing on large cohorts. This study targeted on the genetic causes of childhood epileptic encephalopathy, typically Lennox-Gastaut syndrome (LGS) featured by age-dependent onset and characteristic clinical manifestations. <h4>Methods:</h4> Trio-based whole-exo...

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Literature Corpus work: 88a8ca76-f60d-5ccb-a2ce-be29ade9b9d4
DOI: 10.1101/2023.07.25.23293037

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