Article
Personalized translational epilepsy research - Novel approaches and future perspectives: Part I: Clinical and network analysis approaches.
Epilepsy & behavior : E&B - 1 Nov 2017
Rosenow Felix, van Alphen Natascha, Becker Albert, Chiocchetti Andreas, Deichmann Ralf, Deller Thomas, Freiman Thomas, Freitag Christine M, Gehrig Johannes, Hermsen Anke M, Jedlicka Peter, Kell Christian, Klein Karl Martin, Knake Susanne, Kullmann Dimitri M, Liebner Stefan, Norwood Braxton A, Omigie Diana, Plate Karlheinz, Reif Andreas, Reif Philipp S, Reiss Yvonne, Roeper Jochen, Ronellenfitsch Michael W, Schorge Stephanie, Schratt Gerhard, Schwarzacher Stephan W, Steinbach Joachim P, Strzelczyk Adam, Triesch Jochen, Wagner Marlies, Walker Matthew C, von Wegner Frederic, Bauer Sebastian
Abstract excerpt
Despite the availability of more than 15 new "antiepileptic drugs", the proportion of patients with pharmacoresistant epilepsy has remained constant at about 20-30%. Furthermore, no disease-modifying treatments shown to prevent the development of epilepsy following an initial precipitating brain injury or to reverse established epilepsy have been identified to date. This is likely in part due to the polyetiologic...
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