Article

Urinary bis(monacylglycerol) phosphate (BMP) levels are higher in LRRK2 and GBA1 variant carriers but do not predict disease progression in PPMI cohorts

2022-10-05

Abstract excerpt

<title>Abstract</title> We quantified concentrations of three isoforms of the endolysosomal lipid, bis(monoacylglycerol) phosphate (BMP) in urine of deeply phenotyped cohorts in the Parkinson’s Progression Markers Initiative: <italic>LRRK2</italic> G2019S PD (N = 134) and non-manifesting carriers (NMC) (G2019S + NMC; N = 182), <italic>LRRK2</italic> R1441G PD (N = 15) and R1441G + NMC (N = 15), <italic>GBA1</i...

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Literature Corpus work: 817ba081-d359-58cd-ba42-a999b8af73f7
DOI: 10.21203/rs.3.rs-2065993/v1

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