Article

RAG suppresses group 2 innate lymphoid cells

2024-04-28

Abstract excerpt

<h4>ABSTRACT</h4> Antigen specificity is the central trait distinguishing adaptive from innate immune function. Assembly of antigen-specific T cell and B cell receptors occurs through V(D)J recombination mediated by the Recombinase Activating Gene endonucleases RAG1 and RAG2 (collectively called RAG). In the absence of RAG, mature T and B cells do not develop and thus RAG is critically associated with adaptive im...

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Literature Corpus work: 81696379-f6f0-5db0-ae29-99291bd2e54e
DOI: 10.1101/2024.04.23.590767

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