Article

Micromanipulation of prophase I chromosomes from mouse spermatocytes reveals high stiffness and gel-like chromatin organization

2020-09-01

Abstract excerpt

Meiosis produces four haploid cells after two successive divisions in sexually reproducing organisms. A critical event during meiosis is construction of the synaptonemal complex (SC), a large, protein-based bridge that physically links homologous chromosomes. The SC facilitates meiotic recombination, chromosome compaction, and the eventual separation of homologous chromosomes at metaphase I. We present experiments...

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Literature Corpus work: 8156e34b-d2a5-5418-9d27-98be2d973c77
DOI: 10.1101/2020.08.31.276402

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