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Article

Tissue-specific and spatially dependent metabolic signatures perturbed by injury in skeletally mature male and female mice

2024-09-30

Abstract excerpt

Joint injury is a risk factor for post-traumatic osteoarthritis. However, metabolic and microarchitectural changes within the joint post-injury in both sexes remain unexplored. This study identified tissue-specific and spatially-dependent metabolic signatures in male and female mice using matrix-assisted laser desorption ionization-mass spectrometry imaging (MALDI-MSI) and LC-MS metabolomics. Male and female C57Bl...

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Literature Corpus work
80f33b9b-7d41-5464-8705-57a17f4ad3b6
DOI
10.1101/2024.09.30.615873
Open publication

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Tissue-specific and spatially dependent metabolic signatures perturbed by injury in skeletally mature male and female miceDOI 10.1101/2024.09.30.615873
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