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Integrating untargeted and targeted metabolomics coupled with pathway analysis reveals muscle disorder in osteoporosis on orchiectomized mice

2022-09-28

Abstract excerpt

Most osteoporosis (OP) fracture accidents in men are not only due to low BMD but also because of unhealthy muscle support. However, it has been a limited number of reports about how muscle metabolism is disturbed by OP in male patients. In this work, pathway analysis based on metabolomic research was carried out to fill this gap. Classical orchiectomy procedure was adapted to create OP animal model. Micro-CT and p...

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Literature Corpus work
27793284-d1bc-58d0-a66b-6c93e46d28fc
DOI
10.21203/rs.3.rs-2092562/v1
Open publication

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Integrating untargeted and targeted metabolomics coupled with pathway analysis reveals muscle disorder in osteoporosis on orchiectomized miceDOI 10.21203/rs.3.rs-2092562/v1
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