Article

Recent advances in understanding corticotroph pituitary tumor initiation and progression

2018-08-29

Abstract excerpt

Cushing’s disease is the most frequent form of hypercortisolism and is caused by hypophyseal corticotroph adenomas secreting excessive amounts of adrenocorticotropic hormone. Most of the tumors develop sporadically and only a limited number of corticotroph adenomas have been found to be associated with different neuroendocrine syndromes or with familial isolated pituitary adenomas. The pathogenic mechanisms of cor...

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Literature Corpus work: 80ccfea6-ebef-5478-9b1b-52eea759349e
DOI: 10.12688/f1000research.14789.1

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