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Article

PATHOGENESIS OF CUSHING DISEASE: AN UPDATE ON THE GENETICS OF CORTICOTROPINOMAS.

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists - 2 Oct 2018

Albani Adriana, Perez-Rivas Luis G, Reincke Martin, Theodoropoulou Marily

Abstract excerpt

OBJECTIVE: Cushing disease is a rare severe condition caused by pituitary tumors that secrete adrenocorticotropic hormone (ACTH), leading to excessive endogenous glucocorticoid production. Tumors causing Cushing disease, also called corticotropinomas, are typically monoclonal neoplasms that mainly occur sporadically. METHODS: Literature review. RESULTS: Cushing disease is very rarely encountered in genetic...

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Source

Identifiers

PMID: 30084690
DOI: 10.4158/EP-2018-0111

Genes

USP8
ABL1
CABLES1
CDK5
DICER1
EGFR
POMC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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