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Genome-wide study of gene-by-sex interactions identifies risks for cleft palate

2024-05-03

Abstract excerpt

Structural birth defects affect 3-4% of all live births and, depending on the type, tend to manifest in a sex-biased manner. Orofacial clefts (OFCs) are the most common craniofacial structural birth defects and are often divided into cleft lip with or without cleft palate (CL/P) and cleft palate only (CP). Previous studies have found sex-specific risks for CL/P, but these risks have yet to be evaluated in CP. CL/P...

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Literature Corpus work
80aab250-94ce-5bfd-91ed-af0294de3b71
DOI
10.1101/2024.05.01.24306701
Open publication

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Genome-wide study of gene-by-sex interactions identifies risks for cleft palateDOI 10.1101/2024.05.01.24306701
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