Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Secondary Genome-Wide Association Study Using Novel Analytical Strategies Disentangle Genetic Components of Cleft Lip and/or Cleft Palate in 1q32.2.

Genes - 29 Oct 2020

Yang Yunju, Suzuki Akiko, Iwata Junichi, Jun Goo

Abstract excerpt

Orofacial cleft (OFC) is one of the most prevalent birth defects, leading to substantial and long-term burdens in a newborn's quality of life. Although studies revealed several genetic variants associated with the birth defect, novel approaches may provide additional clues about its etiology. Using the Center for Craniofacial and Dental Genetics project data (n = 10,542), we performed linear mixed-model analyses...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Human, Pair 1
Share to Cleft Lip

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cleft Palate

Share to Genetic Markers

Share to Infant, Newborn

Share to Interferon Regulatory Factors

Share to Linear Models

Share to Microtubule-Associated Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 33137956
DOI: 10.3390/genes11111280
PMCID: PMC7693579

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Secondary Genome-Wide Association Study Using Novel Analytical Strategies Disentangle Genetic Components of Cleft Lip and/or Cleft Palate in 1q32.2.PMID 33137956Read ↗

Rare variants found in clinical gene panels illuminate the genetic and allelic architecture of orofacial cleftingSemantic proximity Read ↗

Variants in CALD1, ESRP1, and RBFOX1 are associated with orofacial cleft risk.Semantic proximity Read ↗

Rare variant modifier analysis identifies variants in SEC24D associated with orofacial cleft subtypes.Semantic proximity Read ↗

Identifying Genetic Sources of Phenotypic Heterogeneity in Orofacial Clefts by Targeted Sequencing.Semantic proximity Read ↗

Rare variants found in clinical gene panels illuminate the genetic and allelic architecture of orofacial clefting.Semantic proximity Read ↗

Progress toward discerning the genetics of cleft lip.Semantic proximity Read ↗

Genetic approaches to identify disease genes for birth defects with cleft lip/palate as a model.Semantic proximity Read ↗

Exploration of Genetic Variants of Non-syndromic Cleft Lip with or without Palate and Underlying Mechanisms.Semantic proximity Read ↗

Identification of shared and unique gene families associated with oral clefts.Semantic proximity Read ↗

Monogenic Versus Multifactorial Inheritance in the Development of Isolated Cleft Palate: A Whole Genome Sequencing StudySemantic proximity Read ↗

Trio-based GWAS reveals novel loci associated with different forms of isolated cleft lipSemantic proximity Read ↗

Genetics of cleft lip and cleft palate.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.