Article

When to Trust Epigenetic Clocks: Avoiding False Positives in Aging Interventions

2024-10-25

Abstract excerpt

Recent human studies have suggested that aging interventions can reduce aging biomarkers related to morbidity and mortality risk. Such biomarkers may potentially serve as early, rapid indicators of effects on healthspan. An increasing number of studies are measuring intervention effects on epigenetic clocks, commonly used aging biomarkers based on DNA methylation profiles. However, with dozens of clocks to choose...

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Literature Corpus work: 6daab614-f052-5412-9de1-29fa22eab79a
DOI: 10.1101/2024.10.22.619720

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