Article

Novel feature selection methods for construction of accurate epigenetic clocks

2022-02-22

Abstract excerpt

Epigenetic clocks allow the accurate prediction of age based on the methylation status of specific CpG sites in a variety of tissues. These predictive models can be used to distinguish the biological age of an organism from its chronological age, and are a powerful tool to measure the effectiveness of aging interventions. There is a growing need for methods to efficiently construct epigenetic clocks. The most comm...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ceb26657-8b01-5366-b586-4de9f9b1c03a
DOI: 10.1101/2022.02.21.481326

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Novel feature selection methods for construction of accurate epigenetic clocksDOI 10.1101/2022.02.21.481326Read

A Network Approach to DNA Methylation ClocksSemantic proximity Read

Recalibrating the epigenetic clock: implications for assessing biological age in the human cortex.Semantic proximity Read

A comparison of feature selection methodologies and learning algorithms in the development of a DNA methylation-based telomere length estimatorSemantic proximity Read

Recalibrating the Epigenetic Clock: Implications for Assessing Biological Age in the Human CortexSemantic proximity Read

AltumAge: A Pan-Tissue DNA-Methylation Epigenetic Clock Based on Deep LearningSemantic proximity Read

Prediction of Biological Age and Blood Biomarkers from DNA Methylation Profiles Measured by the Methylation Screening Array: Development and Validation of Models on Japanese DataSemantic proximity Read

Various diseases and conditions are strongly associated with the next-generation epigenetic aging clock CheekAgeSemantic proximity Read

DNA methylation clocks struggle to distinguish inflammaging from healthy aging, but feature rectification improves coherence and enhances detection of inflammagingSemantic proximity Read

DNA methylation clocks for estimating biological age in Chinese cohortsSemantic proximity Read

Performance of blood-based biomarkers for human circadian pacemaker phase: Training sets matter as much as feature selection methodsSemantic proximity Read

Applicability of epigenetic age models to next-generation methylation arraysSemantic proximity Read

Transfer Elastic Net for Developing Epigenetic Clocks for the Japanese PopulationSemantic proximity Read