Article

A simulation study investigating power estimates in Phenome-Wide Association Studies

2017-03-12

Abstract excerpt

<h4>Background</h4> Phenome-wide association studies (PheWAS) are a high-throughput approach to evaluate comprehensive associations between genetic variants and a wide range of phenotypic measures. PheWAS has varying sample sizes for quantitative traits, and variable numbers of cases and controls for binary traits across the many phenotypes of interest, which can affect the statistical power to detect association...

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Literature Corpus work: 8057da4e-fd9d-5a07-858f-f6ce706096e9
DOI: 10.1101/115550

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