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Article

The effects of case/control ratio and sample size on genome-wide association studies: A simulation study.

Veterinary medicine and science - 1 May 2024

Turgut Ali Osman, Koca Davut

Abstract excerpt

BACKGROUND: Genome-wide association studies (GWAS) is a useful tool for the detection of disease or quantitative trait-related genetic variations in the veterinary field. For a binary trait, a case/control experiment is designed in GWAS. However, there is limited information on the optimal case/control and sample size in GWAS. OBJECTIVES: In this study, it was aimed to detect the effects of case/control ratio and...

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PMID: 38581306
DOI: 10.1002/vms3.1444
PMCID: PMC10998454

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