Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Methodology in phenome-wide association studies: a systematic review.

Journal of medical genetics - 1 Nov 2021

Wang Lijuan, Zhang Xiaomeng, Meng Xiangrui, Koskeridis Fotios, Georgiou Andrea, Yu Lili, Campbell Harry, Theodoratou Evropi, Li Xue

Abstract excerpt

Phenome-wide association study (PheWAS) has been increasingly used to identify novel genetic associations across a wide spectrum of phenotypes. This systematic review aims to summarise the PheWAS methodology, discuss the advantages and challenges of PheWAS, and provide potential implications for future PheWAS studies. Medical Literature Analysis and Retrieval System Online (MEDLINE) and Excerpta Medica Database...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genome-Wide Association Study
Share to Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Single Nucleotide

Share to Quality Control

Share to Sample Size

Share to Software

Source

Identifiers

PMID: 34272311
DOI: 10.1136/jmedgenet-2021-107696

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Methodology in phenome-wide association studies: a systematic review.PMID 34272311Read ↗

[Research progress in the methodology used in phenome-wide association studies].Semantic proximity Read ↗

Maturation and application of phenome-wide association studies.Semantic proximity Read ↗

Phenome-Wide Association Studies.Semantic proximity Read ↗

Phenome-Wide Association Studies as a Tool to Advance Precision Medicine.Semantic proximity Read ↗

Unravelling the human genome-phenome relationship using phenome-wide association studies.Semantic proximity Read ↗

Phenomics: expanding the role of clinical evaluation in genomic studies.Semantic proximity Read ↗

pyPheWAS: A Phenome-Disease Association Tool for Electronic Medical Record Analysis.Semantic proximity Read ↗

Are phenome-wide association studies feasible in a developing country?Semantic proximity Read ↗

PheWAS and Beyond: The Landscape of Associations with Medical Diagnoses and Clinical Measures across 38,662 Individuals from Geisinger.Semantic proximity Read ↗

The use of phenome-wide association studies (PheWAS) for exploration of novel genotype-phenotype relationships and pleiotropy discovery.Semantic proximity Read ↗

Phenome-wide association study (PheWAS) for detection of pleiotropy within the Population Architecture using Genomics and Epidemiology (PAGE) Network.Semantic proximity Read ↗

PhenX: a toolkit for interdisciplinary genetics research.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.