Article

Deregulation of Stemness and Senescence Genes in Bone Marrow Mesenchymal Stem Cells of Multiple Myeloma: Implications for Therapeutic Approaches

2025-10-29

Abstract excerpt

<title>Abstract</title> <p> <bold>Purpose:</bold> Multiple myeloma (MM) is a hematologic malignancy with a poor prognosis. <bold/> MM-derived MSCs (MM-MSCs) contribute to disease progression by creating a supportive stromal microenvironment for malignant cells. Therefore, elucidating transcriptomic alterations in MSCs may facilitate the development of novel therapeutic strategies for treatment <bold/> resis...

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Literature Corpus work: 8046802d-cab3-5c8d-bda5-56bdc2d3d094
DOI: 10.21203/rs.3.rs-7802296/v1

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