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RNA-seq variants reveal distinct patterns in the aging epitranscriptome: an in-depth analysis of age-matched Alzheimer’s Disease patients and a cognitively normal cohort

2026-02-16

Abstract excerpt

<h4>Background</h4> Post-transcriptional modifications are those made to the RNA transcript, which can modulate RNA stability and function. Despite robust investigation of the genome, transcriptome, and proteome, little is known about post-transcriptional modifications during normal aging or Alzheimer’s disease (AD) pathogenesis. Several studies have shown epitranscriptomic changes in AD brains for certain modifi...

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Literature Corpus work
802a9777-bd08-51a6-94a2-c204cc972722
DOI
10.64898/2026.02.14.705891
Open publication

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RNA-seq variants reveal distinct patterns in the aging epitranscriptome: an in-depth analysis of age-matched Alzheimer’s Disease patients and a cognitively normal cohortDOI 10.64898/2026.02.14.705891
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