Article

The impact of genomic structural variation on the transcriptome, chromatin, and proteome in the human brain

2021-02-28

Abstract excerpt

<h4>ABSTRACT</h4> Structural variants (SVs), defined as any genomic rearrangements of 50 or more bp, are an important source of genetic diversity and have been linked to many diseases. However, their contribution to molecular traits in the brain and impact on neurodegenerative diseases remains unknown. Here, we report 170,996 SVs which were constructed using 1,760 short-read whole genomes from aging and Alzheimer’...

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Literature Corpus work: 93d3bd8d-68cd-59eb-8dae-7cd8fd9bf0e4
DOI: 10.1101/2021.02.25.21252245

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