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<i>In vitro</i> plasticity between ureteric epithelial and distal nephron identity and maturity is controlled by extracellular signals

2025-06-03

Abstract excerpt

<h4>Summary</h4> Several studies have described human pluripotent stem cell (hPSC)-derived ureteric epithelium, which in the embryo arises from the nephric duct and forms the collecting ducts of the kidney. However, hPSC-derived distal nephron epithelium can also adopt a ureteric phenotype, despite this not occurring during embryogenesis. In this study, RET tdTomato and GATA3 mCherry reporter lines were used to...

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Literature Corpus work
80129ad7-0fec-53fc-854b-b86faae81bb5
DOI
10.1101/2025.06.03.657609
Open publication

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