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Article

Generation of kidney ureteric bud and collecting duct organoids that recapitulate kidney branching morphogenesis

2020-04-28

Abstract excerpt

Kidney organoids model development and diseases of the nephron but not the contiguous epithelial network of the kidney’s collecting duct (CD) system. Here, we report the generation of an expandable, 3D branching ureteric bud (UB) organoid culture model that can be derived from primary UB progenitors from mouse and human fetal kidneys, or generated de novo from pluripotent human stem cells. UB organoids differenti...

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Identifiers and source

Literature Corpus work
c208fe90-5930-5d2b-8dbb-786de9f21443
DOI
10.1101/2020.04.27.049031
Open publication

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Generation of kidney ureteric bud and collecting duct organoids that recapitulate kidney branching morphogenesisDOI 10.1101/2020.04.27.049031
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