Article

Identification of activity-induced <i>Egr3</i> -dependent genes reveals genes associated with DNA damage response and schizophrenia

2020-09-01

Abstract excerpt

Bioinformatics and network studies have identified the immediate early gene transcription factor early growth response 3 (EGR3) as a master regulator of genes differentially expressed in the brains of patients with neuropsychiatric illnesses ranging from schizophrenia and bipolar disorder to Alzheimer’s disease. However, few studies have identified and validated Egr3 -dependent genes in the mammalian brain. We ha...

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Literature Corpus work: 7fc023a5-8451-55ba-a54d-fa96c558ea71
DOI: 10.1101/2020.09.01.276626

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