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Genetic and functional analyses of early growth response (EGR) family genes in schizophrenia.

Progress in neuro-psychopharmacology & biological psychiatry - 1 Oct 2012

Cheng Min-Chih, Chuang Yang-An, Lu Chao-Lin, Chen Yu-Jung, Luu Sy-Ueng, Li Jun-Ming, Hsu Shih-Hsin, Chen Chia-Hsiang

Abstract excerpt

OBJECTIVE: Early growth response genes (EGR1, 2, 3, and 4) encode a family of nuclear proteins that function as transcriptional regulators. They are involved in the regulation of synaptic plasticity, learning, and memory, and are implicated in the pathogenesis of schizophrenia. METHODS: We conducted a genetic association analysis of 14 SNPs selected from the EGR1, 2, 3, and 4 genes of 564 patients with...

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Source

Identifiers

PMID: 22691714
DOI: 10.1016/j.pnpbp.2012.06.004

Genes

EGR2
EGR4
EGR1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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