Article
Genetic evidence for the association between the early growth response 3 (EGR3) gene and schizophrenia.
PloS one - 1 Jan 2012
Zhang Rui, Lu Shemin, Meng Liesu, Min Zixin, Tian Juan, Valenzuela Robert K, Guo Tingwei, Tian Lifang, Zhao Wenxiang, Ma Jie
Abstract excerpt
Recently, two genome scan meta-analysis studies have found strong evidence for the association of loci on chromosome 8p with schizophrenia. The early growth response 3 (EGR3) gene located in chromosome 8p21.3 was also found to be involved in the etiology of schizophrenia. However, subsequent studies failed to replicate this finding. To investigate the genetic role of EGR3 in Chinese patients, we genotyped four...
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