Article

Anti-inflammatory Role of GM1 and Other Gangliosides on Microglia

2021-08-30

Abstract excerpt

<title>Abstract</title> <p>BackgroundGangliosides are glycosphingolipids highly enriched in the brain, with important roles in cell signaling, cell-to-cell communication, and immunomodulation. Genetic defects in the ganglioside biosynthetic pathway result in severe neurodegenerative diseases, while a partial decrease in the levels of specific gangliosides was reported in Parkinson’s disease and Huntington’s disea...

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Literature Corpus work: 7f9c92d9-30f1-5541-a905-379ea3cb1274
DOI: 10.21203/rs.3.rs-829456/v1

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